Publishing genetic association studies in Thorax

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Publishing genetic association studies in Thorax

G enetic association studies have the potential to provide a valuable insight into disease mechanisms. However, many studies submitted to journals such as Thorax are underpowered or poorly designed. This has led to a number of journals providing guidance to investigators regarding the design of studies which would be considered for publication within the journal. In the editorial which follows ...

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Background and Purpose—A large number of candidate gene association studies have attempted to identify genes implicated in stroke, but there have been few replicable and robust associations reported. Summary of Review—The skantness of replicable associations partly relates to poor study design. Important methodological considerations include adequate sample size, the selection of appropriate co...

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ژورنال

عنوان ژورنال: Thorax

سال: 2005

ISSN: 0040-6376

DOI: 10.1136/thx.2005.043802